HOFFMAN ESTATES, Ill. — Sam Querrey gave the U.S. a commanding 2-0 lead Sept. 12 in its Davis Cup World Group playoff against Slovakia with a 7-6 (6), 6-3, 6-3 win over Martin Klizan.In the opening match of the night, American John Isner hit 29 aces in a 7-6 (5), 6-4, 6-2 win over Norbert Gombos.The U.S. can ensure a trip to the 2015 World Group on Saturday by winning the doubles when it sends out U.S. Open champs Mike and Bob Bryan.“It’s the kind of day you want to have, be comfortable 2-0 with the Bryan brothers coming up,” U.S. captain Jim Courier said. “Both Sam and Jim started off slow but finished strong. Played their best tennis at the end of the match.”Querrey, ranked 51st, faced a set point in the first-set tiebreaker, but responded with two straight aces. He captured the opening set when the 57th-ranked Klizan netted a backhand.Querrey finished with 20 aces on the hard court at the Sears Centre, none bigger than the two he unleashed in the tiebreaker. “It was tough. But my serve is my biggest weapon,” Querrey said. “Just puts the pressure right back on him.”Gombos, ranked 126th, was a surprise choice as Slovakia’s No. 2, but he showed his skills during a group quarterfinal in April when he made his Davis Cup debut and beat Austria’s Dominic Thiem.But this time he had to fight off the powerful serves of Isner and managed only two breakpoint opportunities.“Going into a match like this, three-out-of-five match, it’s not surprising I didn’t lose my serve,” Isner said. “I’ve done that before, for sure. Always going to be the biggest part of my game and it’s going to be the part of my game that I lean on the most.”Isner trailed in the first-set tiebreaker 4-2 before pulling it out 7-5 when Gombos netted a volley and hit long after a strong serve. Isner then broke Gombos in the opening game of the second set and his game improved steadily thereafter.“I was a bit nervous in the beginning. I had to really dig deep to win that first set. But once I got that under my belt, I exhaled and then I started to play better,” Isner said. “It’s never easy. But that first set was very important.”Serving for the second set at 5-4, Isner double-faulted twice but then won the next four points with an ace, a volley, an overhead and a service winner.“I know that he’s serving perfect, like from the Eiffel Tower, you know,” Gombos said. “I never returned a serve like his because it’s quite different from the other players because he is really tall. The ball is bouncing so high.”Isner said he was aware of how well Gombos, who has flat groundstrokes and good speed around the court, can play.“It’s a tough match for someone like me,” Isner said. “We’re at home. I’m ranked higher than him. I guess on paper I’m expected to win that match. There’s a lot of pressure on me. It’s not an easy situation.”The U.S., which lost to Britain earlier this year, hasn’t missed competing in the World Group, the upper tier, since 1988.Slovakia is trying to pull the upset and make it back to the World Group for the first time since 2006.“Well, it’s really tough. I was hoping at least to get one point today. With the better luck we could maybe hope for more,” Slovakia captain Miloslav Mecir said. “But this is the reality.”TweetPinShare0 Shares
Goalkeeper Hannes Halldorsson was a zombie movie director before he started playing football for Iceland. And, it was his experience behind the camera that helped him outwit Argentina’s Lionel Messi on Saturday.Awarded a penalty with the help of VAR, Messi stepped up to take it and it was expected that the Argentina captain will score and put his team ahead. But, the goalkeeper had other plans. Messi unleashed a shot towards the goalkeeper’s right but it was weak and at a saveable height and Halldorsson guessed it right and denied the best player in the world perhaps to add another feather to Iceland’s cap.The tiny nation, which is playing its first World Cup ever, then went on to hold onto the 1-1 scoreline and pull off a major upset in the Group D game.Speaking about his save after the match, he said that he did his homework and it paid off for him.FIFA WORLD CUP 2018 FULL COVERAGE”I did my homework,” the 34-year-old who plays in the Danish league told reporters after stopping a 64th-minute spot kick that pegged Argentina to a 1-1 draw and added to a miserable run of four misses from seven this past season for Messi. Hannes Halldorsson saved a 64th-minute penalty (Reuters Photo)World Cup 2018: Iceland hero reveals how he prepared for Lionel Messi”I looked at a lot of penalties by Messi and I also looked at how I had been behaving in the last penalties. So I tried to get into their mindset, how they would be thinking about me.”advertisement”I had a good feeling it would go this way today,” he said of his dive to his right to stop Messi’s uninspired effort.World Cup 2018: Messi flops as Iceland draw with ArgentinaWith the five-time world player of the year stepping up to restore Argentina’s lead in the Group D opener, tiny Iceland’s first ever appearance at the World Cup finals, Halldorsson admitted that he felt the pressure.Cristiano Ronaldo fans troll Messi over missed penalty”For me, as a goalkeeper from little Iceland and at the first game at a World Cup, to face the best player in the world at a penalty is,” — he gave a long pause — “a big moment.”2018 FIFA WORLD CUP: FULL FIXTURES”It’s a dream come true to save a penalty, especially if it helps us get a big point,” he added, as Iceland now aim to reach the next round from a group also featuring Croatia and Nigeria.World Cup 2018: Modric does what Messi could not as European nations shineHalldorsson is not the only one in the Icelandic unit to have a day job apart from football.Defender Birkir Mar Saevarsson works in a salt-packing factor back home and actually had to take permission from work to play at the World Cup in Russia.Coach Heimir Hallgrimsson promised that more is to come. Satisfied at denying Argentina no space despite 72-percent possession, he even mused on missed chances that might have given victory. Iceland coach Heimir Hallgrimsson (Reuters Photo)But with trademark dark humour, the part-time coach and full-time dentist, conceded: “We wanted to use spaces behind them — but it’s difficult when you don’t have the ball.”Croatia and Nigeria will have to watch out, though.”People say we celebrate when we won a point,” he said. “But wait and see how we celebrate when we’ve won a game.”Nigeria fans barred from carrying chickens into stadiumsIceland will next face Nigeria on June 22 and then cap off their league campaign against Croatia on June 26.
Tottenham Hotspur striker Harry Kane has revealed he’s keen to overtake Pierre-Emerick Aubameyang in the race for the Premier League golden boot award.The England international, who won the Premier League Golden Boot prize in 2016 and 2017 before also finishing first in the race for the Golden boot at the World Cupid Russia, said, according to ESPN: “Since I’ve been in the Premier League it’s had some of the best strikers in the world.”“Aubameyang is at the top end at the moment. There’s quite a few on eight or nine goals so it’s important for me to carry on doing what I’m doing.”“When you’ve done it on the biggest stage of them all, the World Cup, you can look back and gain confidence from that. If you’re going through a spell where you’re not scoring, a couple of games here and there, you know you can do it at the highest level.”Report: Kanu makes bold claim about Pepe George Patchias – September 13, 2019 Former Arsenal superstar Kanu claims the Premier League teams fear Nicolas Pepe.The Ivory Coast international Pepe, made an 80 million Euro move to Arsenal…Spurs victory over Southampton was a welcome relief after Sunday’s 4-2 defeat to Arsenal, and Kane is pleased that the North London side will get another crack at the Unai Emery’s men when they return to the Emirates for the Carabao Cup quarterfinal in two weeks’ time.“It was a derby game and you never want to lose those kinds of games,” he said.“Credit to them, they were probably the better team on the day but it was important for us to dust it off and get back to winning ways.”“Revenge is a strong word but we’ll be motivated [in the quarterfinal]. It was a heated derby. It’s what you want a derby to be like.”“It’s an opportunity for us to get one back if we can. That’s still a couple of weeks away but I’m sure the fans will be looking forward to it, and we will be as well.”
Hundreds attended the 119th Memorial Day ceremony at Fort Rosecrans May 27, 2019 Allie Wagner Categories: Local San Diego News FacebookTwitter Allie Wagner, Hundreds in attendance this morning for the 119th Memorial Day Ceremony at Fort Rosecrans to honor our fallen soldiers @KUSINews @KUSI_GMSD pic.twitter.com/MiLf9Z0e5P— Allie Wagner (@alliewagnertv) May 27, 2019 Remembering those who gave the ultimate sacrifice. They have set up a memorial called Arlington West in front of the @USSMidwayMuseum with 288 markers to honor those who have died. @KUSINews @KUSI_GMSD #memorialday pic.twitter.com/UPpmnPWvkt— Allie Wagner (@alliewagnertv) May 27, 2019 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI) – It is one of San Diego’s largest and most celebrated memorials dedicated to America’s veterans and today Fort Rosecrans National Cemetery hosted its annual Memorial Day celebration.The celebration is hosted by war veterans organizations, their auxiliaries, and patriotic groups.They’ve conducted the Memorial Day services at Fort Rosecrans National Cemetery om San Diego for over 100 years.KUSI’s Allie Wagner has more on this story. Posted: May 27, 2019
More From Roadshow Comments Tags Preview • 2019 Porsche Cayenne: A stronger foundation 2020 Porsche Cayenne Turbo S E-Hybrid first drive: Sweet, sweet overkill SUVs Performance Cars Crossovers More about 2019 Porsche Cayenne 2019 Porsche Cayenne S review: The sporting life Review • 2019 Porsche Cayenne review: The enthusiast’s SUV Share your voice 52 Photos 1:22 A glass roof is standard, but to save weight Coupe buyers can spec out a carbon fiber slab instead as part of a series of “lightweight sports packages” — somewhat curious nomenclature for a vehicle that weighs somewhere north of 4,300 pounds. The carbon roof and the other lightweight tweaks shave about 45 pounds off that figure.Power comes from either of the Cayenne’s pair of engines, starting with the 3.0-liter, turbocharged V6 with 335 horsepower and 332 pound-feet of torque. The Cayenne Coupe Turbo steps up to the 4.0-liter, twin-turbo V8 with 541 horsepower and 567 pound-feet of torque. That’s plenty of power, but other than the more aggressive wheels and standard active suspension, don’t expect the Cayenne Coupe to drive any differently than its normal-bodied cousin. The Coupe has exactly the same suspension hardware and tune, meaning this one’s all about the look.And how much will the look cost you? The starting price of the 2020 Porsche Cayenne Coupe is $75,300. That’s almost $10,000 more than a base Cayenne, but remember you’re getting a few choice options thrown in the mix. The Coupe Turbo, meanwhile, starts at $130,100, and don’t forget the extra $1,250 delivery on both. Look for these Coupes in dealerships this fall, and idling down posh city streets soon thereafter. 2020 Porsche Cayenne spawns a crop-top Coupe 5 things you need to know about the 2020 Porsche Cayenne… Porsche Roll your eyes all you want, readers, the “coupe”-flavor SUV is here to stay. Or, at least, it’s not going away anytime soon. The success of crop-topped high-rollers like the BMW X6 and 2020 Mercedes-Benz GLC Coupe means that others are getting in on the fun, and Porsche’s the latest, unveiling this, the 2020 Cayenne Coupe. Already among the more spirited drives in its category, the Coupe flavor of the Cayenne gets a more purposeful look to match. At its highest, it’s 20 millimeters lower than the regular Cayenne, but the roof sweeps starkly down from there, thoroughly cropping rear headroom and cutting out a good chunk of the rear cargo capacity along the way: 22 cubic feet with the seats up, down from 27.Enlarge ImageThe Coupe’s roof is 20mm lower than the regular Cayenne’s, and reduces rear cargo space from 27 cubic feet to 22. Porsche To help offset the loss of rear headroom, Porsche lowered the rear seats by 30mm. Not enough for me, sadly, as I couldn’t comfortably fit in the back of the Coupe. For reference I have no problem in the regular Cayenne, but then I do sit taller than my 6-foot height might indicate. Most normal humans won’t notice the difference. They will, however, notice the new rear bench, which has a plastic tray separating left and right seats, meaning this is now officially a four-seater. The standard Cayenne’s rear bench is still available as a no-cost option, but the sliding mechanism was nixed in search of that extra 30mm.Optionally, those seats feature inserts wrapped in Porsche’s iconic “pepita” pattern that everyone (including myself) will just keep on calling houndstooth. The Coupe packs more standard features than the regular Cayenne, including sporty choices like PASM active suspension and the Sport Chrono package, plus 20-inch wheels as standard. However, step up to the Cayenne Coupe Turbo and you get 21-inchers at all four corners, with the option of moving up even further to a very comely set of 22-inchers that you can see on the orange car pictured here. The rear bodywork of the Coupe is 18mm wider to accommodate these massive rollers. 2019 Porsche Cayenne E-Hybrid second drive: The best of both worlds 4 Now playing: Watch this: BMW Mercedes-Benz Porsche
Vitamin ‘A’ plus campaign begins. File PhotoThe national Vitamin ‘A’ plus campaign, which was earlier postponed, is being observed across the country today (Saturday), aiming to feed vitamin A plus capsules to all children aged between six and 59 months, reports UNB.Under the campaign, about 2.53 million children aged between six and 11 months will be fed blue coloured vitamin ‘A’ capsules while 19.5 million children aged between 12 and 59 months will be given red coloured high-power capsules.They will be given Vitamin A capsule at some 120,000 permanent and 20,000 mobile health centres across the country.Mobile health centres has been set up at bus stands, railway stations, launch terminals, airports, ferry terminals, bridge toll centres and kheyaghats which will remain open from 8:00am to 4:00pm to make sure that all children are fed the capsules.The children of the remote areas of 240 unions in 42 upazilas of 12 districts will be fed the capsules in the next four days of the campaign day through conducting a search programme.
© 2017 Phys.org Explore further Inspired by natural signaling cascades, chemists have developed synthetic cascades that modify a self-assembled supramolecular structures post-assembly. Researchers from the University of Cambridge have developed a synthetic cascade that is triggered by norbornadiene (NBD) and relayed by a cyclopentadiene (CPD) intermediate resulting in the triggered change of two supramolecular structures. Their work appears in Nature Chemistry.After a one-pot self-assembly of two supramolecular structures, the Nitschke group developed a post-assembly modification (PAM) technique via a covalent signal cascade. PAM reactions are limited by the need to be sufficiently mild that they do not damage the supramolecular structure. They also need to be chemoselective and produce product in near-quantitative yields to eliminate the need for extensive purification and isolation. Diels-Alder reactions are good candidates for these types of reactions.Pilgram, et al. developed a system that underwent inverse-electron demand Diels-Alder (IEDDA) reaction with the initial triggering molecule, NBD, and a tetrazine-edged FeII8L12 cube, and subsequent Diels-Alder reaction with the relay molecule, CPD, and a tetrahedral complex. Their studies verified that the reactions required the triggering molecule and the relay molecule in order to work.Specifically, the synthetic scheme involved first making the terazine-edged cube in a one-pot synthesis. It then underwent the IEDDA reaction between the tetrazines and the NBD trigger molecule. After conducting model reaction tests, they used 2-octadecylnorbornadiene giving a pyridizine-edged cube and a 1-octadecylcyclopentadiene intermediate. This intermediate served as a relay molecule that bound to the maleimides on the tetrahedral complex via a Diels-Alder reaction.In one test, the final reaction involved forming a CPD intermediates with sufficiently long alkyl chains that the tetrahedral product transfers from an organic polar phase to a non-polar phase. Notably, without the initial triggering molecule, the final product is not formed and does not move into the non-polar phase, thus demonstrating a synthetic signal cascade in which a molecule changes lipophilicity as a result of an environmental trigger.Additionally, because the cell’s signal transduction pathways are often regulated by both triggering species as well as inhibitors, the Nitschke group investigated potential inhibitor molecules to their synthetic cascade. They found that cyclooctyne served as a good inhibitor by competitively reacting with the terazine molecules over the NBD trigger.Finally, another key finding of their synthetic cascade is that when the tetrahedral structure is complexed with an anionic guest (PF6-), the guest remains intact even after post-assembly modification of the structure. This allows the guest molecule to be transported from the polar to non-polar phase, which has implications for medicinal and other applications where molecule delivery is hindered by polarity or other environmental features.Dr. Nitschke told PhysOrg that future research includes designing cascades of reactions that are capable of being pushed backwards under out-of-equilibrium conditions. According to Nitschke, “Cascades of out-of-equilibrium reactions that are geared together such that one sequence of reactions either up-regulates or down-regulates another are fundamental building blocks of life. Understanding how they might work could help us understand prebiotic chemistry, as well as help us design complex synthetic assembly lines where substrates are passed along between capsules that chemically modify them.” More information: Ben S. Pilgrim et al. Signal transduction in a covalent post-assembly modification cascade, Nature Chemistry (2017). DOI: 10.1038/nchem.2839AbstractNatural reaction cascades control the movement of biomolecules between cellular compartments. Inspired by these systems, we report a synthetic reaction cascade employing post-assembly modification reactions to direct the partitioning of supramolecular complexes between phases. The system is composed of a self-assembled tetrazine-edged FeII8L12 cube and a maleimide-functionalized FeII4L6 tetrahedron. Norbornadiene (NBD) functions as the stimulus that triggers the cascade, beginning with the inverse-electron-demand Diels–Alder reaction of NBD with the tetrazine moieties of the cube. This reaction generates cyclopentadiene as a transient by-product, acting as a relay signal that subsequently undergoes a Diels–Alder reaction with the maleimide-functionalized tetrahedron. Cyclooctyne can selectively inhibit the cascade by outcompeting NBD as the initial trigger. Initiating the cascade with 2-octadecyl NBD leads to selective alkylation of the tetrahedron upon cascade completion. The increased lipophilicity of the C18-tagged tetrahedron drives this complex into a non-polar phase, allowing its isolation from the initially inseparable mixture of complexes. (Phys.org)—Within the cell chemical messages are passed through a signaling cascade. This cascade can be a series of chemical reactions or molecular changes that spurn the next reaction in a kind of assembly line process. This is how the cell responds to its environment and how communication happens over (biochemically ) long distances. Chemists build new chemical structures on unreactive bonds Citation: Covalent post-assembly modification cascade of self-assembled supramolecular structures (2017, September 6) retrieved 18 August 2019 from https://phys.org/news/2017-09-covalent-post-assembly-modification-cascade-self-assembled.html Depictions (same scale) of the X-ray crystal structures. a, Cube 1b. b, PF6 − adduct of tetrahedron 3. c, AsF6 − adduct of modified tetrahedron 4a. Atom colours: grey, C; white, H; red, O; blue, N; orange, Fe; light green, F. Disorder and non-encapsulated anions are omitted for clarity. Iron atoms are connected with orange lines to illustrate the overall geometry of each complex. Credit: (c) Nature Chemistry (2017). DOI: 10.1038/nchem.2839 Journal information: Nature Chemistry This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. 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Tuesday, April 10, 2018 Share Tags: Go Ahead Tours TORONTO — Increased interest in history tours has prompted EF Go Ahead Tours to develop a curated portfolio of trips centered around remembering Canadian history.The company has partnered with organizations including Canada’s History Magazine and the Juno Beach Centre “to deliver a specialized calibre from a Canadian perspective and add a new level of expertise,” says Johan Astrom, Vice President, Canada, EF Go Ahead Tours.Last year Canadians commemorated the centennial of the Battle of Vimy Ridge. This year they will remember the centenary of the First World War, and in 2019, Canadians will commemorate the 75th anniversary of D-Day.Astrom says agents interested in learning more about EF Go Ahead Tours’ portfolio of history tours, or working with clients interested in learning more about Canada’s role in the World Wars or have a family connection, are encouraged to contact EF Go Ahead Tours for more information.“Our team of tour consultants are here to answer any questions you might have, or speak to the tour experience as a whole,” he says.In 2017 EF Go Ahead Tours took travellers on a Vimy Ridge Centennial Tour. “The response to that tour, and the emotional connection that so many of our travellers experienced while standing among nearly 25,000 fellow Canadians memorializing the battle, really reinforced our ambitions to develop a more extensive portfolio of tours that celebrates Canada’s role in some of the events that helped shape history,” said Astrom.More news: Visit Orlando unveils new travel trade tools & agent perksThe company’s portfolio of upcoming tours includes:Canada’s Great War Album – On this exclusive tour, 35 travellers will be immersed in the narrative of this historic region by travelling on this specially curated tour, created in partnership with Canada’s History Magazine. Participants will journey alongside Mark Reid, Editor-in-Chief of Canada’s History and author of ‘Canada’s Great War Album’, as they make their way from the Vimy region to the Normandy Coast.Departure: Aug. 24, 2018Length: 10 days (12 with extension)D-Day 75th Anniversary: London, Normandy & Amsterdam – Along the coast of Normandy and through the streets of London and Amsterdam, the influence of WWII can still be felt. Visit memorials, trenches, and museums and learn about the important role Canadian forces played in the outcome of D-Day.Departures: June 2, 2019 and Nov. 6, 2019Length: 12 days (15 with extension)Canadian WWII History: The Italian Campaign – This trip focuses on the role of Canadian forces during the Italian Campaign. Make your way through the small towns and waterfront cities of Monte Cassino, Ortona, and Rimini to see the backdrop for some of the most important events of WWII. Experience deep history and endless beauty on this tour through Italy.Departures: May 29, 2019 and Nov. 7, 2019Length: 12 days (14 with extension)Canadian World War History: Vimy to Juno Beach – Set out from Amsterdam to cross the former battlefields of the Netherlands, Belgium, and France, where soldiers gave their lives during the First and Second World Wars. Visit historic sites and memorials in Lille, Ypres, and along the coast of Normandy before the journey ends in Paris.Departures: May 11, 2018; Sept. 21, 2018; Oct. 12, 2018; May 10, 2019 and Sept. 20, 2019Length: 10 days (12 with extension)More news: Can you guess the top Instagrammed wedding locations in the world?Agents can call 1-800-719-9805 or visit goaheadtours.ca. Posted by Travelweek Group << Previous PostNext Post >> EF Go Ahead Tours offers history tours with Canadian expertise